HELPING THE OTHERS REALIZE THE ADVANTAGES OF PKRRATING

3B). R526 with the loop concerning αJ and αI anchors the C-terminal part of the activation loop by forming a salt bridge with E458 at the base of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the principle chain carbonyl of R413. The tip on the activation phase is stabilized by a hydrogen bond amongst Y454 and E480 from αF. during th

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